Article-Journal

Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing.
Neuroserpin is a serine-protease inhibitor mainly expressed in the CNS and involved in the inhibition of the proteolytic cascade. …
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New insights into the development of the human cerebral cortex.
The cerebral cortex constitutes more than half the volume of the human brain and is presumed to be responsible for the neuronal …
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Immature excitatory neurons develop during adolescence in the human amygdala.
The human amygdala grows during childhood, and its abnormal development is linked to mood disorders. The primate amygdala contains a …
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Shared and derived features of cellular diversity in the human cerebral cortex.
The cerebral cortex is the hallmark of the mammalian nervous system, and its large size and cellular diversity in humans support our …
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Single-cell genomics identifies cell type-specific molecular changes in autism.
Despite the clinical and genetic heterogeneity of autism, bulk gene expression studies show that changes in the neocortex of autism …
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Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.
In the developing human neocortex, progenitor cells generate diverse cell types prenatally. Progenitor cells and newborn neurons …
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Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution.
Direct comparisons of human and non-human primate brains can reveal molecular pathways underlying remarkable specializations of the …
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Does Adult Neurogenesis Persist in the Human Hippocampus?

PubMed ID: 30526879

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Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development.
MicroRNAs (miRNAs) regulate many cellular events during brain development by interacting with hundreds of mRNA transcripts. However, …
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Identification of cell types in a mouse brain single-cell atlas using low sampling coverage.
BACKGROUND: High throughput methods for profiling the transcriptomes of single cells have recently emerged as transformative approaches …
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