Kriegstein Lab
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Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors.
Glycine and gamma-aminobutyric acid, type A (GABA(A)) receptors are members of the ligand-gated ion channel superfamily that mediate …
Ivic L
,
Sands TT
,
Fishkin N
,
Nakanishi K
,
Arnold R Kriegstein, MD, PhD
,
Stromgaard K
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DOI
Radial glia diversity: a matter of cell fate.
Early in development of the central nervous system, radial glial cells arise from the neuroepithelial cells lining the ventricles …
Arnold R Kriegstein, MD, PhD
,
Gotz M
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DOI
Changing concepts of cortical development.
PubMed ID:
12764026
Kriegstein A
,
Parnavelas JG
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DOI
Neurogenic radial glial cells in reptile, rodent and human: from mitosis to migration.
Radial glial cells play at least two crucial roles in cortical development: neuronal production in the ventricular zone (VZ) and the …
Weissman T
,
Noctor SC
,
Clinton BK
,
Honig LS
,
Arnold R Kriegstein, MD, PhD
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DOI
Neurons from radial glia: the consequences of asymmetric inheritance.
Recent work suggests that radial glial cells represent many, if not most, of the neuronal progenitors in the developing cortex. …
Fishell G
,
Arnold R Kriegstein, MD, PhD
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DOI
Developmental neurotransmitters?
Previous studies support an early role for neurotransmitter signaling before synaptogenesis, but puzzlingly, a neurological phenotype …
Owens DF
,
Arnold R Kriegstein, MD, PhD
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DOI
Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex.
PURPOSE: Cortical dysplasia (CD) is associated with epilepsy in both the pediatric and adult populations. The mechanism underlying …
Benardete EA
,
Arnold R Kriegstein, MD, PhD
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DOI
Is there more to GABA than synaptic inhibition?
In the mature brain, GABA (gamma-aminobutyric acid) functions primarily as an inhibitory neurotransmitter. But it can also act as a …
Owens DF
,
Arnold R Kriegstein, MD, PhD
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DOI
Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia.
The embryonic ventricular zone (VZ) of the cerebral cortex contains migrating neurons, radial glial cells, and a large population of …
Noctor SC
,
Flint AC
,
Weissman TA
,
Wong WS
,
Clinton BK
,
Arnold R Kriegstein, MD, PhD
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DOI
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