Kriegstein Lab
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The temporal and spatial origins of cortical interneurons predict their physiological subtype.
Interneurons of the cerebral cortex represent a heterogeneous population of cells with important roles in network function. At present, …
Butt SJ
,
Fuccillo M
,
Nery S
,
Noctor S
,
Kriegstein A
,
Corbin JG
,
Fishell G
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DOI
LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages.
Mutations in the human LIS1 gene cause the smooth brain disease classical lissencephaly. To understand the underlying mechanisms, we …
Tsai JW
,
Chen Y
,
Arnold R Kriegstein, MD, PhD
,
Vallee RB
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DOI
GABA puts the brake on stem cells.
PubMed ID:
16127444
Arnold R Kriegstein, MD, PhD
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DOI
Cortical development: new concepts.
PubMed ID:
15882631
Fishell G
,
Kriegstein A
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DOI
A new era in the ethics of human embryonic stem cell research.
Scientific progress in human embryonic stem cell (hESC) research and increased funding make it imperative to look ahead to the ethical …
Lo B
,
Zettler P
,
Cedars MI
,
Gates E
,
Arnold R Kriegstein, MD, PhD
,
Oberman M
,
Reijo Pera R
,
Wagner RM
,
Wuerth MT
,
Wolf LE
,
Yamamoto KR
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DOI
Constructing circuits: neurogenesis and migration in the developing neocortex.
Our knowledge of the proliferation, migration, and differentiation of neurons has changed dramatically over the last 10 years. Whereas …
Arnold R Kriegstein, MD, PhD
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DOI
Calcium waves propagate through radial glial cells and modulate proliferation in the developing neocortex.
The majority of neurons in the adult neocortex are produced embryonically during a brief but intense period of neuronal proliferation. …
Weissman TA
,
Riquelme PA
,
Ivic L
,
Flint AC
,
Arnold R Kriegstein, MD, PhD
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DOI
Controlling neuron number: does Numb do the math?
PubMed ID:
15280888
Castaneda-Castellanos DR
,
Arnold R Kriegstein, MD, PhD
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DOI
Patterns of neuronal migration in the embryonic cortex.
Real-time imaging of migrating neurons has changed our understanding of how newborn neurons reach their final positions in the …
Arnold R Kriegstein, MD, PhD
,
Noctor SC
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DOI
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases.
Precise patterns of cell division and migration are crucial to transform the neuroepithelium of the embryonic forebrain into the adult …
Noctor SC
,
Martinez-Cerdeno V
,
Ivic L
,
Arnold R Kriegstein, MD, PhD
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DOI
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