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Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats.
We investigated a strategy to ameliorate the motor symptoms of rats that received 6-hydroxydopamine (6-OHDA) lesions, a rodent model of …
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Regenerative medicine: Cell reprogramming gets direct.

PubMed ID: 20182502

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Research ethics. NIH guidelines for stem cell research and gamete donors.

PubMed ID: 20167773

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Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.
The use of iPSCs and tetraploid complementation for human reproductive cloning would raise profound ethical objections. Professional …
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Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex.
Asymmetric cell division of radial glial progenitors produces neurons while allowing self-renewal; however, little is known about the …
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A stem cell niche for intermediate progenitor cells of the embryonic cortex.
The excitatory neurons of the mammalian cerebral cortex arise from asymmetric divisions of radial glial cells in the ventricular zone …
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Defining the role of GABA in cortical development.
Of the many signals in the developing nervous system, GABA (gamma-aminobutyric acid) has been shown to be one of the earliest …
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Commentary: the prospect of cell-based therapy for epilepsy.
About 30% of patient with epilepsy do not respond to available antiepileptic drugs. In addition to seizure suppression, novel …
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Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns.
Stem cell researchers commonly use human pluripotent stem cell lines derived by other investigators. Researchers may use lines derived …
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The glial nature of embryonic and adult neural stem cells.
Glial cells were long considered end products of neural differentiation, specialized supportive cells with an origin very different …
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